Para‐Fluorination of Anilides Using Electrochemically Generated Hypervalent Iodoarenes

The para‐selective fluorination reaction of anilides using electrochemically generated hypervalent ArIF(2) is reported, with Et(3)N ⋅ 5HF serving as fluoride source and as supporting electrolyte. This electrochemical reaction is characterized by a simple set‐up, easy scalability and affords a broad...

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Detalles Bibliográficos
Autores principales: Berger, Michael, Lenhard, Marola S., Waldvogel, Siegfried R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9401020/
https://www.ncbi.nlm.nih.gov/pubmed/35510825
http://dx.doi.org/10.1002/chem.202201029
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author Berger, Michael
Lenhard, Marola S.
Waldvogel, Siegfried R.
author_facet Berger, Michael
Lenhard, Marola S.
Waldvogel, Siegfried R.
author_sort Berger, Michael
collection PubMed
description The para‐selective fluorination reaction of anilides using electrochemically generated hypervalent ArIF(2) is reported, with Et(3)N ⋅ 5HF serving as fluoride source and as supporting electrolyte. This electrochemical reaction is characterized by a simple set‐up, easy scalability and affords a broad variety of fluorinated anilides from easily accessible anilides in good yields up to 86 %.
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spelling pubmed-94010202022-08-26 Para‐Fluorination of Anilides Using Electrochemically Generated Hypervalent Iodoarenes Berger, Michael Lenhard, Marola S. Waldvogel, Siegfried R. Chemistry Research Articles The para‐selective fluorination reaction of anilides using electrochemically generated hypervalent ArIF(2) is reported, with Et(3)N ⋅ 5HF serving as fluoride source and as supporting electrolyte. This electrochemical reaction is characterized by a simple set‐up, easy scalability and affords a broad variety of fluorinated anilides from easily accessible anilides in good yields up to 86 %. John Wiley and Sons Inc. 2022-06-07 2022-07-20 /pmc/articles/PMC9401020/ /pubmed/35510825 http://dx.doi.org/10.1002/chem.202201029 Text en © 2022 The Authors. Chemistry - A European Journal published by Wiley-VCH GmbH https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Research Articles
Berger, Michael
Lenhard, Marola S.
Waldvogel, Siegfried R.
Para‐Fluorination of Anilides Using Electrochemically Generated Hypervalent Iodoarenes
title Para‐Fluorination of Anilides Using Electrochemically Generated Hypervalent Iodoarenes
title_full Para‐Fluorination of Anilides Using Electrochemically Generated Hypervalent Iodoarenes
title_fullStr Para‐Fluorination of Anilides Using Electrochemically Generated Hypervalent Iodoarenes
title_full_unstemmed Para‐Fluorination of Anilides Using Electrochemically Generated Hypervalent Iodoarenes
title_short Para‐Fluorination of Anilides Using Electrochemically Generated Hypervalent Iodoarenes
title_sort para‐fluorination of anilides using electrochemically generated hypervalent iodoarenes
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9401020/
https://www.ncbi.nlm.nih.gov/pubmed/35510825
http://dx.doi.org/10.1002/chem.202201029
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