Cargando…
Functionalised Cofactor Mimics for Interactome Discovery and Beyond
Cofactors are required for almost half of all enzyme reactions, but their functions and binding partners are not fully understood even after decades of research. Functionalised cofactor mimics that bind in place of the unmodified cofactor can provide answers, as well as expand the scope of cofactor...
Autores principales: | Wilkinson, Isabel V. L., Pfanzelt, Martin, Sieber, Stephan A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9401033/ https://www.ncbi.nlm.nih.gov/pubmed/35286003 http://dx.doi.org/10.1002/anie.202201136 |
Ejemplares similares
-
Customizing Functionalized Cofactor Mimics to Study the Human Pyridoxal 5′-Phosphate-Binding Proteome
por: Fux, Anja, et al.
Publicado: (2019) -
Mining the cellular inventory of pyridoxal phosphate-dependent enzymes with functionalized cofactor mimics
por: Hoegl, Annabelle, et al.
Publicado: (2018) -
Tailored Pyridoxal Probes Unravel Novel Cofactor‐Dependent Targets and Antibiotic Hits in Critical Bacterial Pathogens
por: Pfanzelt, Martin, et al.
Publicado: (2022) -
Oxygenating Biocatalysts for Hydroxyl Functionalisation in Drug Discovery and Development
por: Charlton, Sacha N., et al.
Publicado: (2022) -
Tick Importin-α Is Implicated in the Interactome and Regulome of the Cofactor Subolesin
por: Artigas-Jerónimo, Sara, et al.
Publicado: (2021)