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Commonly Used Alkylating Agents Limit Persulfide Detection by Converting Protein Persulfides into Thioethers
Protein persulfides (R‐S‐SH) have emerged as a common post‐translational modification. Detection and quantitation of protein persulfides requires trapping with alkylating agents. Here we show that alkylating agents differ dramatically in their ability to conserve the persulfide's sulfur–sulfur...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9401046/ https://www.ncbi.nlm.nih.gov/pubmed/35506673 http://dx.doi.org/10.1002/anie.202203684 |