Binding mechanism of oseltamivir and influenza neuraminidase suggests perspectives for the design of new anti-influenza drugs

Oseltamivir is a widely used influenza virus neuraminidase (NA) inhibitor that prevents the release of new virus particles from host cells. However, oseltamivir-resistant strains have emerged, but effective drugs against them have not yet been developed. Elucidating the binding mechanisms between NA...

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Detalles Bibliográficos
Autores principales: Tao, Jiaye, Wang, Heping, Wang, Wenjian, Mi, Na, Zhang, Wei, Wen, Qiujia, Ouyang, Jiajing, Liang, Xinyun, Chen, Min, Guo, Wentao, Li, Guoming, Liu, Jun, Zhao, Hanning, Wang, Xin, Li, Xuemeng, Feng, Shengjun, Liu, Xinguang, He, Zhiwei, Zhao, Zuguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9401145/
https://www.ncbi.nlm.nih.gov/pubmed/35901128
http://dx.doi.org/10.1371/journal.pcbi.1010343

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