Pharmacogenomics Testing Confirmation of Carbamazepine Induced DRESS Reaction of an HLA-A*31:01 Positive, Polypharmacy Patient

Pharmacogenomics (PGx) melds well with polypharmacy as another tool to identify medication related problems (MRPs) more specifically so they may be solved most effectively. PGx can pre-emptively assist in medication selection, medication dosing or identify better medications for patients already tak...

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Detalles Bibliográficos
Autores principales: Speicher, Leigh, Crosby, Sheena, Schuh, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: University of Minnesota Libraries Publishing 2021
Materias:
Case Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9401381/
https://www.ncbi.nlm.nih.gov/pubmed/36033112
http://dx.doi.org/10.24926/iip.v12i4.4341
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author Speicher, Leigh
Crosby, Sheena
Schuh, Michael J.
author_facet Speicher, Leigh
Crosby, Sheena
Schuh, Michael J.
author_sort Speicher, Leigh
collection PubMed
description Pharmacogenomics (PGx) melds well with polypharmacy as another tool to identify medication related problems (MRPs) more specifically so they may be solved most effectively. PGx can pre-emptively assist in medication selection, medication dosing or identify better medications for patients already taking a medication. PGx can also confirm suspect medications of causing MRPs such as adverse drug reactions (ADRs) or drug interactions. In this case, PGx testing confirmed presence of a serious human leukocyte antigen (HLA) drug reaction with eosinophilia and systemic symptoms (DRESS) after a suspect medication had been stopped.
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spelling pubmed-94013812022-08-25 Pharmacogenomics Testing Confirmation of Carbamazepine Induced DRESS Reaction of an HLA-A*31:01 Positive, Polypharmacy Patient Speicher, Leigh Crosby, Sheena Schuh, Michael J. Innov Pharm Case Study Pharmacogenomics (PGx) melds well with polypharmacy as another tool to identify medication related problems (MRPs) more specifically so they may be solved most effectively. PGx can pre-emptively assist in medication selection, medication dosing or identify better medications for patients already taking a medication. PGx can also confirm suspect medications of causing MRPs such as adverse drug reactions (ADRs) or drug interactions. In this case, PGx testing confirmed presence of a serious human leukocyte antigen (HLA) drug reaction with eosinophilia and systemic symptoms (DRESS) after a suspect medication had been stopped. University of Minnesota Libraries Publishing 2021-09-22 /pmc/articles/PMC9401381/ /pubmed/36033112 http://dx.doi.org/10.24926/iip.v12i4.4341 Text en © Individual authors https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial License, which permits noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Study
Speicher, Leigh
Crosby, Sheena
Schuh, Michael J.
Pharmacogenomics Testing Confirmation of Carbamazepine Induced DRESS Reaction of an HLA-A*31:01 Positive, Polypharmacy Patient
title Pharmacogenomics Testing Confirmation of Carbamazepine Induced DRESS Reaction of an HLA-A*31:01 Positive, Polypharmacy Patient
title_full Pharmacogenomics Testing Confirmation of Carbamazepine Induced DRESS Reaction of an HLA-A*31:01 Positive, Polypharmacy Patient
title_fullStr Pharmacogenomics Testing Confirmation of Carbamazepine Induced DRESS Reaction of an HLA-A*31:01 Positive, Polypharmacy Patient
title_full_unstemmed Pharmacogenomics Testing Confirmation of Carbamazepine Induced DRESS Reaction of an HLA-A*31:01 Positive, Polypharmacy Patient
title_short Pharmacogenomics Testing Confirmation of Carbamazepine Induced DRESS Reaction of an HLA-A*31:01 Positive, Polypharmacy Patient
title_sort pharmacogenomics testing confirmation of carbamazepine induced dress reaction of an hla-a*31:01 positive, polypharmacy patient
topic Case Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9401381/
https://www.ncbi.nlm.nih.gov/pubmed/36033112
http://dx.doi.org/10.24926/iip.v12i4.4341
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