Darolutamide Potentiates the Antitumor Efficacy of a PSMA-targeted Thorium-227 Conjugate by a Dual Mode of Action in Prostate Cancer Models

PURPOSE: Androgen receptor (AR) inhibitors are well established in the treatment of castration-resistant prostate cancer and have recently shown efficacy also in castration-sensitive prostate cancer. Although most patients respond well to initial therapy, resistance eventually develops, and thus, mo...

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Detalles Bibliográficos
Autores principales: Hammer, Stefanie, Schlicker, Andreas, Zitzmann-Kolbe, Sabine, Baumgart, Simon, Hagemann, Urs B., Scholz, Arne, Haendler, Bernard, Lejeune, Pascale, Karlsson, Jenny, Ellingsen, Christine, Hennekes, Hartwig, Nielsen, Carsten H., Juul, Mark U., Mumberg, Dominik, Schatz, Christoph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2021
Materias:
Translational Cancer Mechanisms and Therapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9401501/
https://www.ncbi.nlm.nih.gov/pubmed/34035067
http://dx.doi.org/10.1158/1078-0432.CCR-21-0342

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