Ovarian Cancer–Specific BRCA-like Copy-Number Aberration Classifiers Detect Mutations Associated with Homologous Recombination Deficiency in the AGO-TR1 Trial

PURPOSE: Previously, we developed breast cancer BRCA1-like and BRCA2-like copy-number profile shrunken centroid classifiers predictive for mutation status and response to therapy, targeting homologous recombination deficiency (HRD). Therefore, we investigated BRCA1- and BRCA2-like classification in...

Descripción completa

Detalles Bibliográficos
Autores principales: Schouten, Philip C., Richters, Lisa, Vis, Daniel J., Kommoss, Stefan, van Dijk, Ewald, Ernst, Corinna, Kluin, Roelof J.C., Marmé, Frederik, Lips, Esther H., Schmidt, Sandra, Scheerman, Esther, Prieske, Katharina, van Deurzen, Carolien H.M., Burges, Alexander, Ewing-Graham, Patricia C., Dietrich, Dimo, Jager, Agnes, de Gregorio, Nikolaus, Hauke, Jan, du Bois, Andreas, Nederlof, Petra M., Wessels, Lodewyk F., Hahnen, Eric, Harter, Philipp, Linn, Sabine C., Schmutzler, Rita K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2021
Materias:
Translational Cancer Mechanisms and Therapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9401539/
https://www.ncbi.nlm.nih.gov/pubmed/34593530
http://dx.doi.org/10.1158/1078-0432.CCR-21-1673

Ejemplares similares

Ejemplares similares