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Mogamulizumab in Combination with Nivolumab in a Phase I/II Study of Patients with Locally Advanced or Metastatic Solid Tumors

PURPOSE: The aim of the study was to determine safety, antitumor activity, and pharmacodynamic profile of mogamulizumab, an anti-CCR4 monoclonal antibody targeting effector regulatory T cells (Treg) in combination with the checkpoint inhibitor nivolumab in patients with locally advanced or metastati...

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Detalles Bibliográficos
Autores principales:	Hong, David S., Rixe, Olivier, Chiu, Vi K., Forde, Patrick M., Dragovich, Tomislav, Lou, Yanyan, Nayak-Kapoor, Asha, Leidner, Rom, Atkins, James N., Collaku, Agron, Fox, Floyd E., Marshall, Margaret A., Olszanski, Anthony J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for Cancer Research 2022
Materias:	Clinical Trials: Immunotherapy
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9401557/ https://www.ncbi.nlm.nih.gov/pubmed/34753777 http://dx.doi.org/10.1158/1078-0432.CCR-21-2781

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