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Total Synthesis and Prediction of Ulodione Natural Products Guided by DFT Calculations

A biomimetic synthetic strategy has resulted in a two‐step total synthesis of (±)‐ulodione A and the prediction of two potential natural products, (±)‐ulodiones C and D. This work was guided by computational investigations into the selectivity of a proposed biosynthetic Diels–Alder dimerization, whi...

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Detalles Bibliográficos
Autores principales: Bestwick, Jacob S., Jones, David J., Jones, Helen E., Kalomenopoulos, Panagiotis G., Szabla, Rafal, Lawrence, Andrew L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9401604/
https://www.ncbi.nlm.nih.gov/pubmed/35670364
http://dx.doi.org/10.1002/anie.202207004

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