Engineering of hybrid spheroids of mesenchymal stem cells and drug depots for immunomodulating effect in islet xenotransplantation

Immunomodulation is an essential consideration for cell replacement procedures. Unfortunately, lifelong exposure to nonspecific systemic immunosuppression results in immunodeficiency and has toxic effects on nonimmune cells. Here, we engineered hybrid spheroids of mesenchymal stem cells (MSCs) with...

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Detalles Bibliográficos
Autores principales: Nguyen, Tiep Tien, Pham, Duc-Vinh, Park, Junhyeung, Phung, Cao Dai, Nepal, Mahesh Raj, Pandit, Mahesh, Shrestha, Manju, Son, Youlim, Joshi, Mili, Jeong, Tae Cheon, Park, Pil-Hoon, Choi, Dong-Young, Chang, Jae-Hoon, Kim, Ju-Hyun, Kim, Jae-Ryong, Kim, Il-Kug, Yong, Chul Soon, Kim, Jong Oh, Sung, Jong-Hyuk, Jiang, Hu-Lin, Kim, Hyung-Sik, Yook, Simmyung, Jeong, Jee-Heon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9401619/
https://www.ncbi.nlm.nih.gov/pubmed/36001671
http://dx.doi.org/10.1126/sciadv.abn8614

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