DLL4 and VCAM1 enhance the emergence of T cell–competent hematopoietic progenitors from human pluripotent stem cells

T cells show tremendous efficacy as cellular therapeutics. However, obtaining primary T cells from human donors is expensive and variable. Pluripotent stem cells (PSCs) have the potential to provide a renewable source of T cells, but differentiating PSCs into hematopoietic progenitors with T cell po...

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Detalles Bibliográficos
Autores principales: Michaels, Yale S., Edgar, John M., Major, Matthew C., Castle, Elizabeth L., Zimmerman, Carla, Yin, Ting, Hagner, Andrew, Lau, Charles, Hsu, Han Hsuan, Ibañez-Rios, M. Iliana, Durland, Lauren J., Knapp, David J. H. F., Zandstra, Peter W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9401626/
https://www.ncbi.nlm.nih.gov/pubmed/36001668
http://dx.doi.org/10.1126/sciadv.abn5522

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