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A lipid nanoparticle platform for mRNA delivery through repurposing of cationic amphiphilic drugs

Since the recent clinical approval of siRNA-based drugs and COVID-19 mRNA vaccines, the potential of RNA therapeutics for patient healthcare has become widely accepted. Lipid nanoparticles (LNPs) are currently the most advanced nanocarriers for RNA packaging and delivery. Nevertheless, the intracell...

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Detalles Bibliográficos
Autores principales:	Bogaert, Bram, Sauvage, Félix, Guagliardo, Roberta, Muntean, Cristina, Nguyen, Van Phuc, Pottie, Eline, Wels, Mike, Minnaert, An-Katrien, De Rycke, Riet, Yang, Qiangbing, Peer, Dan, Sanders, Niek, Remaut, Katrien, Paulus, Yannis M., Stove, Christophe, De Smedt, Stefaan C., Raemdonck, Koen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Published by Elsevier B.V. 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9401634/ https://www.ncbi.nlm.nih.gov/pubmed/35963467 http://dx.doi.org/10.1016/j.jconrel.2022.08.009

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