Second Coordination Sphere Effects on the Mechanistic Pathways for Dioxygen Activation by a Ferritin: Involvement of a Tyr Radical and the Identification of a Cation Binding Site

Ferritins are ubiquitous diiron enzymes involved in iron(II) detoxification and oxidative stress responses and can act as metabolic iron stores. The overall reaction mechanisms of ferritin enzymes are still unclear, particularly concerning the role of the conserved, near catalytic center Tyr residue...

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Detalles Bibliográficos
Autores principales: Yeh, Chieh‐Chih George, Mokkawes, Thirakorn, Bradley, Justin M., Le Brun, Nick E., de Visser, Sam P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9401865/
https://www.ncbi.nlm.nih.gov/pubmed/35510795
http://dx.doi.org/10.1002/cbic.202200257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9401865/
https://www.ncbi.nlm.nih.gov/pubmed/35510795
http://dx.doi.org/10.1002/cbic.202200257

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