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Stereocontrolled Synthesis of Fluorinated Isochromans via Iodine(I)/Iodine(III) Catalysis

The success of saturated, fluorinated heterocycles in contemporary drug discovery provides a stimulus for creative endeavor in main group catalysis. Motivated by the ubiquity of isochromans across the bioactive small molecule spectrum, the prominence of the anomeric effect in regulating conformation...

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Detalles Bibliográficos
Autores principales: Häfliger, Joel, Sokolova, Olga O., Lenz, Madina, Daniliuc, Constantin G., Gilmour, Ryan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9401867/
https://www.ncbi.nlm.nih.gov/pubmed/35536157
http://dx.doi.org/10.1002/anie.202205277

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