Soluble MAC is primarily released from MAC-resistant bacteria that potently convert complement component C5

The membrane attack complex (MAC or C5b-9) is an important effector of the immune system to kill invading microbes. MAC formation is initiated when complement enzymes on the bacterial surface convert complement component C5 into C5b. Although the MAC is a membrane-inserted complex, soluble forms of...

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Detalles Bibliográficos
Autores principales: Doorduijn, Dennis J, Lukassen, Marie V, van 't Wout, Marije FL, Franc, Vojtech, Ruyken, Maartje, Bardoel, Bart W, Heck, Albert JR, Rooijakkers, Suzan HM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9402229/
https://www.ncbi.nlm.nih.gov/pubmed/35947526
http://dx.doi.org/10.7554/eLife.77503

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