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Alzheimer's Amyloid-β Accelerates Cell Senescence and Suppresses the SIRT1/NRF2 Pathway in Human Microglial Cells

Microglia play important roles in maintenance of brain homeostasis, while due to some pathological stimuli in aging-related neurodegenerative diseases including Alzheimer's disease, they are malfunctioning. Here, we demonstrated that amyloid-β (Aβ) accelerated cell senescence characterized by t...

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Detalles Bibliográficos
Autores principales:	An, Yuqian, Li, Yi, Hou, Yujun, Huang, Shichao, Pei, Gang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9402294/ https://www.ncbi.nlm.nih.gov/pubmed/36035216 http://dx.doi.org/10.1155/2022/3086010

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