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PtdIns4P on Dispersed Trans-Golgi Network Mediates NLRP3 Inflammasome Activation
The NLRP3 inflammasome, which has been linked to human inflammatory diseases, is activated by a plethora of stimuli. How NLRP3 is activated by such diverse stimuli is a central question that is unresolved. Here we show that different NLRP3 stimuli lead to a hitherto unknown disassembly of trans-Golg...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9402428/ https://www.ncbi.nlm.nih.gov/pubmed/30487600 http://dx.doi.org/10.1038/s41586-018-0761-3 |