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Reconstitution of a telomeric replicon organized by CST
Telomeres, the natural ends of linear chromosomes, comprise repeat-sequence DNA and associated proteins(1). Replication of telomeres allows continued proliferation of human stem cells and immortality of cancer cells(2). This replication requires telomerase(3) extension of the single-stranded DNA (ss...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9402439/ https://www.ncbi.nlm.nih.gov/pubmed/35831508 http://dx.doi.org/10.1038/s41586-022-04930-8 |