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Reconstitution of a telomeric replicon organized by CST

Telomeres, the natural ends of linear chromosomes, comprise repeat-sequence DNA and associated proteins(1). Replication of telomeres allows continued proliferation of human stem cells and immortality of cancer cells(2). This replication requires telomerase(3) extension of the single-stranded DNA (ss...

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Detalles Bibliográficos
Autores principales:	Zaug, Arthur J., Goodrich, Karen J., Song, Jessica J., Sullivan, Ashley E., Cech, Thomas R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9402439/ https://www.ncbi.nlm.nih.gov/pubmed/35831508 http://dx.doi.org/10.1038/s41586-022-04930-8

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