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Adjusting Overall Survival Estimates of Macitentan in Pulmonary Arterial Hypertension After Treatment Switching: Results from the SERAPHIN Study
INTRODUCTION: Evaluating overall survival in randomized controlled trials (RCTs) can often be confounded by bias introduced by treatment switching. SERAPHIN was a large RCT that evaluated the effects of long-term treatment with the endothelin receptor antagonist macitentan in patients with pulmonary...
Autores principales: | Di Scala, Lilla, Bacchi, Marisa, Bayer, Bjørn, Turricchia, Stefano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Healthcare
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9402487/ https://www.ncbi.nlm.nih.gov/pubmed/35917059 http://dx.doi.org/10.1007/s12325-022-02253-8 |
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