In silico validation of RNA-Seq results can identify gene fusions with oncogenic potential in glioblastoma

RNA-Sequencing (RNA-Seq) can identify gene fusions in tumors, but not all these fusions have functional consequences. Using multiple data bases, we have performed an in silico analysis of fusions detected by RNA-Seq in tumor samples from 139 newly diagnosed glioblastoma patients to identify in-frame...

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Detalles Bibliográficos
Autores principales: Hernandez, Ainhoa, Muñoz-Mármol, Ana Maria, Esteve-Codina, Anna, Alameda, Francesc, Carrato, Cristina, Pineda, Estela, Arpí-Lluciá, Oriol, Martinez-García, Maria, Mallo, Mar, Gut, Marta, del Barco, Sonia, Gallego, Oscar, Dabad, Marc, Mesia, Carlos, Bellosillo, Beatriz, Domenech, Marta, Vidal, Noemí, Aldecoa, Iban, de la Iglesia, Nuria, Balana, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9402576/
https://www.ncbi.nlm.nih.gov/pubmed/36002559
http://dx.doi.org/10.1038/s41598-022-18608-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9402576/
https://www.ncbi.nlm.nih.gov/pubmed/36002559
http://dx.doi.org/10.1038/s41598-022-18608-8

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