Optimized scaling of translational factors in oncology: from xenografts to RECIST

PURPOSE: Tumor growth inhibition (TGI) models are regularly used to quantify the PK–PD relationship between drug concentration and in vivo efficacy in oncology. These models are typically calibrated with data from xenograft mice and before being used for clinical predictions, translational methods h...

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Detalles Bibliográficos
Autores principales: Baaz, Marcus, Cardilin, Tim, Lignet, Floriane, Jirstrand, Mats
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9402719/
https://www.ncbi.nlm.nih.gov/pubmed/35922568
http://dx.doi.org/10.1007/s00280-022-04458-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9402719/
https://www.ncbi.nlm.nih.gov/pubmed/35922568
http://dx.doi.org/10.1007/s00280-022-04458-8

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