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Optimized scaling of translational factors in oncology: from xenografts to RECIST
PURPOSE: Tumor growth inhibition (TGI) models are regularly used to quantify the PK–PD relationship between drug concentration and in vivo efficacy in oncology. These models are typically calibrated with data from xenograft mice and before being used for clinical predictions, translational methods h...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9402719/ https://www.ncbi.nlm.nih.gov/pubmed/35922568 http://dx.doi.org/10.1007/s00280-022-04458-8 |