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Long-Term Safety, Tolerability and Survival in Patients with Pulmonary Arterial Hypertension Treated with Macitentan: Results from the SERAPHIN Open-Label Extension
INTRODUCTION: In SERAPHIN, a long-term, event-driven, double-blind randomised controlled trial in pulmonary arterial hypertension (PAH), macitentan 10 mg significantly reduced the risk of morbidity/mortality compared with placebo. Its open-label extension study (SERAPHIN OL) further assessed long-te...
Autores principales: | Souza, Rogério, Delcroix, Marion, Galié, Nazzareno, Jansa, Pavel, Mehta, Sanjay, Pulido, Tomás, Rubin, Lewis, Sastry, B. K. S., Simonneau, Gérald, Sitbon, Olivier, Torbicki, Adam, Boyanova, Neli, Chamitava, Liliya, Stein, Claudia, Channick, Richard N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Healthcare
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9402744/ https://www.ncbi.nlm.nih.gov/pubmed/35819570 http://dx.doi.org/10.1007/s12325-022-02199-x |
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