Wnt Signaling Pathways: A Role in Pain Processing

The wingless-related integration site (Wnt) signaling pathway plays an essential role in embryonic development and nervous system regulation. It is critically involved in multiple types of neuropathic pain (NP), such as HIV-related NP, cancer pain, diabetic neuralgia, multiple sclerosis-related NP,...

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Autores principales: Tang, Yiting, Chen, Yupeng, Liu, Rui, Li, Weidong, Hua, Baojin, Bao, Yanju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9402773/
https://www.ncbi.nlm.nih.gov/pubmed/35067780
http://dx.doi.org/10.1007/s12017-021-08700-z
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author Tang, Yiting
Chen, Yupeng
Liu, Rui
Li, Weidong
Hua, Baojin
Bao, Yanju
author_facet Tang, Yiting
Chen, Yupeng
Liu, Rui
Li, Weidong
Hua, Baojin
Bao, Yanju
author_sort Tang, Yiting
collection PubMed
description The wingless-related integration site (Wnt) signaling pathway plays an essential role in embryonic development and nervous system regulation. It is critically involved in multiple types of neuropathic pain (NP), such as HIV-related NP, cancer pain, diabetic neuralgia, multiple sclerosis-related NP, endometriosis pain, and other painful diseases. Wnt signaling is also implicated in the pain induced by sciatic nerve compression injury and selective spinal nerve ligation. Thus, the Wnt signaling pathway may be a potential therapeutic target for NP.
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spelling pubmed-94027732022-08-26 Wnt Signaling Pathways: A Role in Pain Processing Tang, Yiting Chen, Yupeng Liu, Rui Li, Weidong Hua, Baojin Bao, Yanju Neuromolecular Med Review The wingless-related integration site (Wnt) signaling pathway plays an essential role in embryonic development and nervous system regulation. It is critically involved in multiple types of neuropathic pain (NP), such as HIV-related NP, cancer pain, diabetic neuralgia, multiple sclerosis-related NP, endometriosis pain, and other painful diseases. Wnt signaling is also implicated in the pain induced by sciatic nerve compression injury and selective spinal nerve ligation. Thus, the Wnt signaling pathway may be a potential therapeutic target for NP. Springer US 2022-01-24 2022 /pmc/articles/PMC9402773/ /pubmed/35067780 http://dx.doi.org/10.1007/s12017-021-08700-z Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Review
Tang, Yiting
Chen, Yupeng
Liu, Rui
Li, Weidong
Hua, Baojin
Bao, Yanju
Wnt Signaling Pathways: A Role in Pain Processing
title Wnt Signaling Pathways: A Role in Pain Processing
title_full Wnt Signaling Pathways: A Role in Pain Processing
title_fullStr Wnt Signaling Pathways: A Role in Pain Processing
title_full_unstemmed Wnt Signaling Pathways: A Role in Pain Processing
title_short Wnt Signaling Pathways: A Role in Pain Processing
title_sort wnt signaling pathways: a role in pain processing
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9402773/
https://www.ncbi.nlm.nih.gov/pubmed/35067780
http://dx.doi.org/10.1007/s12017-021-08700-z
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AT huabaojin wntsignalingpathwaysaroleinpainprocessing
AT baoyanju wntsignalingpathwaysaroleinpainprocessing

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