Cargando…

Short-term efficacy and safety of a lower dose of polyethylene glycol recombinant human growth hormone in children with growth hormone deficiency: A randomized, dose-comparison study

Objective: Polyethylene glycol recombinant human growth hormone (PEG-rhGH, Jintrolong(®)) is the first long-acting rhGH preparation that is approved to treat children with growth hormone deficiency (GHD) in China. Clinical experience with dose selections of PEG-rhGH is scarce. The present study comp...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jiang, Zhouhong, Chen, Xuefeng, Dong, Guanping, Lou, Yin, Zhang, Jianping, Cheng, Xinran, Pan, Jiayan, Liao, Wei, Wu, Jinzhun, Huang, Xiaodong, Jin, Xianjiang, Liu, Deyun, Zeng, Ting, Zhu, Shunye, Dong, Qin, Luo, Xiaoming, Lan, Dan, Cao, Lizhi, Zhang, Xingxing, Liu, Jing, Dai, Mingjuan, Zhang, Manyan, Liu, Li, Dong, Junhua, Zhao, Dongmei, Ni, Shaoqing, Fu, Junfen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9402941/ https://www.ncbi.nlm.nih.gov/pubmed/36034802 http://dx.doi.org/10.3389/fphar.2022.955809

Ejemplares similares

Metabolomic Differential Compounds Reflecting the Clinical Efficacy of Polyethylene Glycol Recombinant Human Growth Hormone in the Treatment of Childhood Growth Hormone Deficiency
por: Li, Ji, et al.
Publicado: (2022)

An examination of the effects of different doses of recombinant human growth hormone on children with growth hormone deficiency
por: XUE, YING, et al.
Publicado: (2016)

Effects of different doses of long-acting growth hormone in treating children with growth hormone deficiency
por: Xia, Wei, et al.
Publicado: (2023)

Growth hormone replacement therapy in adults with growth hormone deficiency; thrice weekly low dose administration.
por: Chung, Y. S., et al.
Publicado: (1994)

Comparative Study of the Effects of Different Growth Hormone Doses on Growth and Spatial Performance of Hypophysectomized Rats
por: Kwak, Min Jung, et al.
Publicado: (2009)

Comparative pharmacokinetics and pharmacodynamics of a PEGylated recombinant human growth hormone and daily recombinant human growth hormone in growth hormone-deficient children
por: Hou, Ling, et al.
Publicado: (2015)

Dose-Effect of Zearalenone on the Localization and Expression of Growth Hormone, Growth Hormone Receptor, and Heat Shock Protein 70 in the Ovaries of Post-weaning Gilts
por: Song, Tingting, et al.
Publicado: (2021)

Growth Hormone Response to L-Arginine Alone and Combined with Different Doses of Growth Hormone-Releasing Hormone: A Systematic Review and Meta-Analysis
por: Goli, Parvin, et al.
Publicado: (2022)

Long-acting PEGylated recombinant human growth hormone (Jintrolong) for children with growth hormone deficiency: phase II and phase III multicenter, randomized studies
por: Luo, Xiaoping, et al.
Publicado: (2017)

The Use of Morning Urinary Gonadotropins and Sex Hormones in the Management of Early Puberty in Chinese Girls
por: Zhan, Shumin, et al.
Publicado: (2021)

Attenuation of Human Growth Hormone-Induced Rash With Graded Dose Challenge
por: Mann, Jake, et al.
Publicado: (2022)

A Real-World Study of Recombinant Human Growth Hormone in the Treatment of Idiopathic Short Stature and Growth Hormone Deficiency
por: Gou, Peng, et al.
Publicado: (2022)

The effects of recombinant human growth hormone therapy on thyroid function in pediatric patients with growth hormone deficiency
por: Yao, Qian, et al.
Publicado: (2021)

Insulin sensitivity in long-lived growth hormone-releasing hormone knockout mice
por: Zhang, Fang, et al.
Publicado: (2020)

Growth hormone response to growth hormone-releasing peptide-2 in growth hormone-deficient Little mice
por: Peroni, Cibele N., et al.
Publicado: (2012)

Porcine growth hormone induces the nuclear localization of porcine growth hormone receptor in vivo
por: Lan, Hainan, et al.
Publicado: (2018)

Different thresholds of tissue-specific dose-responses to growth hormone in short prepubertal children
por: Decker, Ralph, et al.
Publicado: (2012)

Response to low dose growth hormone treatment in infants and toddlers with Prader-Willi Syndrome
por: Scheermeyer, Elly, et al.
Publicado: (2015)

Effects of a local single dose administration of growth hormone on the osseointegration of titanium implants
por: Grossi, João Ricardo Almeida, et al.
Publicado: (2022)

Growth Hormone Dosing Estimations Based on Body Weight Versus Body Surface Area
por: Besci, Özge, et al.
Publicado: (2023)

Thyroid Hormone Changes Related to Growth Hormone Therapy in Growth Hormone Deficient Patients
por: Kucharska, Anna Małgorzata, et al.
Publicado: (2021)

Growth Hormone-Releasing Hormone in Diabetes
por: Fridlyand, Leonid E., et al.
Publicado: (2016)

Sex Hormones, Growth Hormone, and the Cornea
por: McKay, Tina B., et al.
Publicado: (2022)

Polyethylene glycol recombinant human growth hormone in Chinese prepubertal slow-growing short children: doses reported in a multicenter real-world study
por: Chen, Jiajia, et al.
Publicado: (2022)

Growth hormone treatment in non-growth hormone-deficient children
por: Loche, Sandro, et al.
Publicado: (2014)

Multiple Effects of Growth Hormone in the Body: Is it Really the Hormone for Growth?
por: Devesa, Jesús, et al.
Publicado: (2016)

Effect of Vitamin D Combined with Recombinant Human Growth Hormone in Children with Growth Hormone Deficiency
por: Wang, Pingping, et al.
Publicado: (2022)

Impact of BMI on peak growth hormone responses to provocative tests and therapeutic outcome in children with growth hormone deficiency
por: Yang, Aram, et al.
Publicado: (2019)

Atrazine Binds to the Growth Hormone–Releasing Hormone Receptor and Affects Growth Hormone Gene Expression
por: Fakhouri, Walid D., et al.
Publicado: (2010)

Model informed quantification of the feed‐forward stimulation of growth hormone by growth hormone‐releasing hormone
por: van Esdonk, Michiel J., et al.
Publicado: (2020)

Long-term Pegylated GH for Children With GH Deficiency: A Large, Prospective, Real-world Study
por: Hou, Ling, et al.
Publicado: (2023)

Actively separated microneedle patch for sustained-release of growth hormone to treat growth hormone deficiency
por: Yang, Li, et al.
Publicado: (2023)

Growth hormone response to submaximal doses of ghrelin remains unchanged during the follicular phase of the cycle
por: Messini, Christina I, et al.
Publicado: (2013)

Adult Heights of 258 Girls with Turner Syndrome on Low Dose of Growth Hormone Therapy in Japan
por: Fujita, Keinosuke, et al.
Publicado: (2010)

Growth hormone (GH) dose-dependent IGF-I response relates to pubertal height gain
por: Lundberg, Elena, et al.
Publicado: (2015)

Growth Hormone-Releasing Hormone in Lung Physiology and Pulmonary Disease
por: Zhang, Chongxu, et al.
Publicado: (2020)

Structural basis for activation of the growth hormone-releasing hormone receptor
por: Zhou, Fulai, et al.
Publicado: (2020)

The Decreased Growth Hormone Response to Growth Hormone Releasing Hormone in Obesity Is Associated to Cardiometabolic Risk Factors
por: Cordido, Fernando, et al.
Publicado: (2010)

Canine growth hormone.
por: Wilhelmi, A. E.
Publicado: (1968)

Growth Hormone in Humans
por: Bondy, Philip K.
Publicado: (1954)

Cannot write session to /tmp/vufind_sessions/sess_2orijbp0j9g5537cufuf5ia6ks