Identifying Novel Drug Targets by iDTPnd: A Case Study of Kinase Inhibitors

Current FDA-approved kinase inhibitors cause diverse adverse effects, some of which are due to the mechanism-independent effects of these drugs. Identifying these mechanism-independent interactions could improve drug safety and support drug repurposing. Here, we develop iDTPnd (integrated Drug Targe...

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Detalles Bibliográficos
Autores principales: Naveed, Hammad, Reglin, Corinna, Schubert, Thomas, Gao, Xin, Arold, Stefan T., Maitland, Michael L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403029/
https://www.ncbi.nlm.nih.gov/pubmed/33794377
http://dx.doi.org/10.1016/j.gpb.2020.05.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403029/
https://www.ncbi.nlm.nih.gov/pubmed/33794377
http://dx.doi.org/10.1016/j.gpb.2020.05.006

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