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Cardiac complications from multisystem inflammatory syndrome associated with prior COVID-19 infection

Multisystem inflammatory syndrome in adults (MIS-A) is a systemic inflammatory condition that presents roughly 4–6 weeks after initial COVID-19 infection. Patients typically present with persistent fevers, widespread rash, abdominal pain, vomiting and diarrhoea, and new-onset neurological symptoms....

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Autores principales: Patel, Krishna, Mehta, Rahul, Betz, Yaqub M, Man, Louise M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403161/
https://www.ncbi.nlm.nih.gov/pubmed/35999019
http://dx.doi.org/10.1136/bcr-2022-249889
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author Patel, Krishna
Mehta, Rahul
Betz, Yaqub M
Man, Louise M
author_facet Patel, Krishna
Mehta, Rahul
Betz, Yaqub M
Man, Louise M
author_sort Patel, Krishna
collection PubMed
description Multisystem inflammatory syndrome in adults (MIS-A) is a systemic inflammatory condition that presents roughly 4–6 weeks after initial COVID-19 infection. Patients typically present with persistent fevers, widespread rash, abdominal pain, vomiting and diarrhoea, and new-onset neurological symptoms. Cardiac dysfunction is a prominent feature of COVID-19 sequelae due to the abundance of ACE2 receptors on cardiac tissue. Delayed diagnosis due to the novelty of MIS-A can lead to cardiac complications like heart failure and shock, which could result in chronic cardiac disease. Avoidance of complications and chronic illness is possible with prompt corticosteroid therapy. Despite patient recovery to baseline level of function, surveillance of cardiac function to screen for chronic cardiac disease in the follow-up period is recommended. We present a case of MIS-A in a young man, compare his presentation with other similar cases and discuss implications of delayed diagnosis.
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spelling pubmed-94031612022-09-06 Cardiac complications from multisystem inflammatory syndrome associated with prior COVID-19 infection Patel, Krishna Mehta, Rahul Betz, Yaqub M Man, Louise M BMJ Case Rep Case Reports: Learning from unexpected outcome (positive or negative) Multisystem inflammatory syndrome in adults (MIS-A) is a systemic inflammatory condition that presents roughly 4–6 weeks after initial COVID-19 infection. Patients typically present with persistent fevers, widespread rash, abdominal pain, vomiting and diarrhoea, and new-onset neurological symptoms. Cardiac dysfunction is a prominent feature of COVID-19 sequelae due to the abundance of ACE2 receptors on cardiac tissue. Delayed diagnosis due to the novelty of MIS-A can lead to cardiac complications like heart failure and shock, which could result in chronic cardiac disease. Avoidance of complications and chronic illness is possible with prompt corticosteroid therapy. Despite patient recovery to baseline level of function, surveillance of cardiac function to screen for chronic cardiac disease in the follow-up period is recommended. We present a case of MIS-A in a young man, compare his presentation with other similar cases and discuss implications of delayed diagnosis. BMJ Publishing Group 2022-08-23 /pmc/articles/PMC9403161/ /pubmed/35999019 http://dx.doi.org/10.1136/bcr-2022-249889 Text en © BMJ Publishing Group Limited 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle Case Reports: Learning from unexpected outcome (positive or negative)
Patel, Krishna
Mehta, Rahul
Betz, Yaqub M
Man, Louise M
Cardiac complications from multisystem inflammatory syndrome associated with prior COVID-19 infection
title Cardiac complications from multisystem inflammatory syndrome associated with prior COVID-19 infection
title_full Cardiac complications from multisystem inflammatory syndrome associated with prior COVID-19 infection
title_fullStr Cardiac complications from multisystem inflammatory syndrome associated with prior COVID-19 infection
title_full_unstemmed Cardiac complications from multisystem inflammatory syndrome associated with prior COVID-19 infection
title_short Cardiac complications from multisystem inflammatory syndrome associated with prior COVID-19 infection
title_sort cardiac complications from multisystem inflammatory syndrome associated with prior covid-19 infection
topic Case Reports: Learning from unexpected outcome (positive or negative)
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403161/
https://www.ncbi.nlm.nih.gov/pubmed/35999019
http://dx.doi.org/10.1136/bcr-2022-249889
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