Genotoxicity Evaluation of Metformin in Freshwater Planarian Dugesia japonica by the Comet Assay and RAPD Analysis

OBJECTIVE: To investigate the genotoxicity of metformin on planarian with different concentrations and exposure times. METHODS: The planarians were treated, respectively, with 10 mmol/L and 50 mmol/L metformin for 1, 3, and 5 days, and then, the comet assay and random amplified polymorphic DNA (RAPD...

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Detalles Bibliográficos
Autores principales: Yin, Dandan, Xu, Zhenbiao, Feng, Minmin, Zhao, Zelong, Chen, Dahu, Song, Linxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403254/
https://www.ncbi.nlm.nih.gov/pubmed/36033573
http://dx.doi.org/10.1155/2022/2822605

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403254/
https://www.ncbi.nlm.nih.gov/pubmed/36033573
http://dx.doi.org/10.1155/2022/2822605

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