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Genotoxicity Evaluation of Metformin in Freshwater Planarian Dugesia japonica by the Comet Assay and RAPD Analysis

OBJECTIVE: To investigate the genotoxicity of metformin on planarian with different concentrations and exposure times. METHODS: The planarians were treated, respectively, with 10 mmol/L and 50 mmol/L metformin for 1, 3, and 5 days, and then, the comet assay and random amplified polymorphic DNA (RAPD...

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Detalles Bibliográficos
Autores principales:	Yin, Dandan, Xu, Zhenbiao, Feng, Minmin, Zhao, Zelong, Chen, Dahu, Song, Linxia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403254/ https://www.ncbi.nlm.nih.gov/pubmed/36033573 http://dx.doi.org/10.1155/2022/2822605

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