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Obstacles for T-lymphocytes in the tumour microenvironment: Therapeutic challenges, advances and opportunities beyond immune checkpoint

The tumour microenvironment (TME) imposes a major obstacle to infiltrating T-lymphocytes and suppresses their function. Several immune checkpoint proteins that interfere with ligand/receptor interactions and impede T-cell anti-tumour responses have been identified. Immunotherapies that block immune...

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Detalles Bibliográficos
Autores principales:	Verma, Navin Kumar, Wong, Brandon Han Siang, Poh, Zhi Sheng, Udayakumar, Aiswarya, Verma, Ritu, Goh, Ryan Kwang Jin, Duggan, Shane P., Shelat, Vishalkumar G., Chandy, K. George, Grigoropoulos, Nicholas Francis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403334/ https://www.ncbi.nlm.nih.gov/pubmed/35986950 http://dx.doi.org/10.1016/j.ebiom.2022.104216

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