Cargando…

Transcriptome-wide association study of HIV-1 acquisition identifies HERC1 as a susceptibility gene

The host genetic factors conferring protection against HIV type 1 (HIV-1) acquisition remain elusive, and in particular the contributions of common genetic variants. Here, we performed the largest genome-wide association meta-analysis of HIV-1 acquisition, which included 7,303 HIV-1-positive individ...

Descripción completa

Detalles Bibliográficos
Autores principales:	Duarte, Rodrigo R.R., Pain, Oliver, Furler, Robert L., Nixon, Douglas F., Powell, Timothy R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403347/ https://www.ncbi.nlm.nih.gov/pubmed/36034232 http://dx.doi.org/10.1016/j.isci.2022.104854

Ejemplares similares

The Downregulation of Both Giant HERCs, HERC1 and HERC2, Is an Unambiguous Feature of Chronic Myeloid Leukemia, and HERC1 Levels Are Associated with Leukemic Cell Differentiation
por: Ali, Muhammad Shahzad, et al.
Publicado: (2022)

HERCing: Structural and Functional Relevance of the Large HERC Ubiquitin Ligases
por: García-Cano, Jesús, et al.
Publicado: (2019)

HERC Ubiquitin Ligases in Cancer
por: Sala-Gaston, Joan, et al.
Publicado: (2020)

The behavioral, cellular and immune mediators of HIV-1 acquisition: New insights from population genetics
por: Powell, Timothy R., et al.
Publicado: (2020)

Rapid Evolution of HERC6 and Duplication of a Chimeric HERC5/6 Gene in Rodents and Bats Suggest an Overlooked Role of HERCs in Mammalian Immunity
por: Jacquet, Stéphanie, et al.
Publicado: (2020)

HERC1 Regulates Breast Cancer Cells Migration and Invasion
por: Rossi, Fabiana Alejandra, et al.
Publicado: (2021)

HERC1 Ubiquitin Ligase Is Required for Hippocampal Learning and Memory
por: Pérez-Villegas, Eva M., et al.
Publicado: (2020)

The HERC1 ubiquitin ligase regulates presynaptic membrane dynamics of central synapses
por: Montes-Fernández, Mª Angeles, et al.
Publicado: (2020)

Large HERCs Function as Tumor Suppressors
por: Schneider, Taiane, et al.
Publicado: (2019)

The expression and clinical significance of HERC4 in breast cancer
por: Zhou, Hui, et al.
Publicado: (2013)

HERC2/USP20 coordinates CHK1 activation by modulating CLASPIN stability
por: Zhu, Min, et al.
Publicado: (2014)

SAV1, regulated by HERC4, inhibits the proliferation, migration, and invasion of hepatocellular carcinoma
por: Huang, Fang, et al.
Publicado: (2021)

Association between Variants in the OCA2-HERC2 Region and Blue Eye Colour in HERC2 rs12913832 AA and AG Individuals
por: Salvo, Nina Mjølsnes, et al.
Publicado: (2023)

Human HERC5 restricts an early stage of HIV-1 assembly by a mechanism correlating with the ISGylation of Gag
por: Woods, Matthew W, et al.
Publicado: (2011)

Ditching candidate gene association studies: lessons from psychiatric genetics
por: Duarte, Rodrigo R.R., et al.
Publicado: (2021)

Endothelial SIRT1 prevents adverse arterial remodeling by facilitating HERC2-mediated degradation of acetylated LKB1
por: Bai, Bo, et al.
Publicado: (2016)

A global view of the OCA2-HERC2 region and pigmentation
por: Donnelly, Michael P., et al.
Publicado: (2011)

Transcriptome-wide association study identifies novel candidate susceptibility genes for migraine
por: Meyers, Travis J., et al.
Publicado: (2023)

HERC1 deficiency causes osteopenia through transcriptional program dysregulation during bone remodeling
por: Pedrazza, Leonardo, et al.
Publicado: (2023)

The ZZ domain of HERC2 is a receptor of arginylated substrates
por: Tencer, Adam H., et al.
Publicado: (2022)

Regulation of MAPK Signaling Pathways by the Large HERC Ubiquitin Ligases
por: Sala-Gaston, Joan, et al.
Publicado: (2023)

HIV-1 replication and latency are balanced by mTOR-driven cell metabolism
por: Crater, Jacqueline M., et al.
Publicado: (2022)

Transcriptome-wide association study identifies susceptibility genes for rheumatoid arthritis
por: Wu, Cuiyan, et al.
Publicado: (2021)

Identifying susceptibility genes for essential hypertension by transcriptome-wide association study
por: Huang, Lu-jie, et al.
Publicado: (2022)

EHD1 promotes CP110 ubiquitination by centriolar satellite delivery of HERC2 to the mother centriole
por: Xie, Shuwei, et al.
Publicado: (2023)

New and novel intrinsic host repressive factors against HIV-1: PAF1 complex, HERC5 and others
por: Tyagi, Mudit, et al.
Publicado: (2012)

HERC5 and the ISGylation Pathway: Critical Modulators of the Antiviral Immune Response
por: Mathieu, Nicholas A., et al.
Publicado: (2021)

Zebrafish HERC7c Acts as an Inhibitor of Fish IFN Response
por: Li, Yi-Lin, et al.
Publicado: (2023)

NRF2 controls iron homeostasis and ferroptosis through HERC2 and VAMP8
por: Anandhan, Annadurai, et al.
Publicado: (2023)

Epigenetic control of alternative mRNA processing at the imprinted Herc3/Nap1l5 locus
por: Cowley, Michael, et al.
Publicado: (2012)

Combinatory effect of BRCA1 and HERC2 expression on outcome in advanced non-small-cell lung cancer
por: Bonanno, Laura, et al.
Publicado: (2016)

The E3 ubiquitin ligase HERC1 controls the ERK signaling pathway targeting C-RAF for degradation
por: Schneider, Taiane, et al.
Publicado: (2018)

A miRNA-HERC4 pathway promotes breast tumorigenesis by inactivating tumor suppressor LATS1
por: Xu, Youqin, et al.
Publicado: (2019)

Transcriptome-wide association study of multiple myeloma identifies candidate susceptibility genes
por: Went, Molly, et al.
Publicado: (2019)

A transcriptome-wide association study identifies susceptibility genes for Parkinson’s disease
por: Yao, Shi, et al.
Publicado: (2021)

Transcriptome-wide association study identifies new susceptibility genes and pathways for depression
por: Li, Xiaoyan, et al.
Publicado: (2021)

Transcriptome‐wide association analysis identified candidate susceptibility genes for nasopharyngeal carcinoma
por: He, Yong‐Qiao, et al.
Publicado: (2022)

Genome- and Transcriptome-Wide Association Studies Identify Susceptibility Genes and Pathways for Periodontitis
por: Zhu, Guirong, et al.
Publicado: (2022)

Transcriptome-wide association study identifies new susceptibility genes and pathways for spondyloarthritis
por: Su, Xiaochen, et al.
Publicado: (2023)

Proteomic Analysis and Identification of Cellular Interactors of the Giant Ubiquitin Ligase HERC2
por: Galligan, Jeffrey T., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_t6krkpjb00o0r2nc8rtgeo48an