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P2X7 receptor blockade decreases inflammation, apoptosis, and enteric neuron loss during Clostridioides difficile toxin A-induced ileitis in mice

BACKGROUND: Clostridioides difficile (C. difficile) is the most common pathogen causing health care-associated infections. C. difficile TcdA and TcdB have been shown to activate enteric neurons; however, what population of these cells is more profoundly influenced and the mechanism underlying these...

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Detalles Bibliográficos
Autores principales:	Santos, Ana A Q A, Costa, Deiziane V S, Foschetti, Danielle A, Duarte, Antoniella S G, Martins, Conceição S, Soares, Pedro M G, Castelucci, Patricia, Brito, Gerly A C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Baishideng Publishing Group Inc 2022
Materias:	Basic Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403433/ https://www.ncbi.nlm.nih.gov/pubmed/36157120 http://dx.doi.org/10.3748/wjg.v28.i30.4075

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