Long-term culture of patient-derived cardiac organoids recapitulated Duchenne muscular dystrophy cardiomyopathy and disease progression

Duchenne Muscular Dystrophy (DMD) is an X-linked neuromuscular disease which to date is incurable. The major cause of death is dilated cardiomyopathy however, its pathogenesis is unclear as existing cellular and animal models do not fully recapitulate the human disease phenotypes. In this study, we...

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Detalles Bibliográficos
Autores principales: Marini, Vittoria, Marino, Fabiola, Aliberti, Flaminia, Giarratana, Nefele, Pozzo, Enrico, Duelen, Robin, Cortés Calabuig, Álvaro, La Rovere, Rita, Vervliet, Tim, Torella, Daniele, Bultynck, Geert, Sampaolesi, Maurilio, Chai, Yoke Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403515/
https://www.ncbi.nlm.nih.gov/pubmed/36035984
http://dx.doi.org/10.3389/fcell.2022.878311

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