Histone lysine demethylase inhibition reprograms prostate cancer metabolism and mechanics

OBJECTIVE: Aberrant activity of androgen receptor (AR) is the primary cause underlying development and progression of prostate cancer (PCa) and castration-resistant PCa (CRPC). Androgen signaling regulates gene transcription and lipid metabolism, facilitating tumor growth and therapy resistance in e...

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Detalles Bibliográficos
Autores principales: Chianese, Ugo, Papulino, Chiara, Passaro, Eugenia, Evers, Tom MJ., Babaei, Mehrad, Toraldo, Antonella, De Marchi, Tommaso, Niméus, Emma, Carafa, Vincenzo, Nicoletti, Maria Maddalena, Del Gaudio, Nunzio, Iaccarino, Nunzia, Randazzo, Antonio, Rotili, Dante, Mai, Antonello, Cappabianca, Salvatore, Mashaghi, Alireza, Ciardiello, Fortunato, Altucci, Lucia, Benedetti, Rosaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403566/
https://www.ncbi.nlm.nih.gov/pubmed/35944897
http://dx.doi.org/10.1016/j.molmet.2022.101561

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