Fe(iii)-catalysed selective C–N bond cleavage of N-phenylamides by an electrochemical method

An Fe(iii)-catalysed transformation of secondary N-phenyl substituted amides to primary amides by an electrochemical method is developed. Regioselective aryl C–H oxygenation occurs during the reaction, promoting selective C(phenyl)-N bond cleavage to form primary amides in yields of up to 92%.

Detalles Bibliográficos
Autores principales: Xu, Yiwen, Long, Yang, Ye, Runyou, Li, Qiang, Ke, Fang, Zhou, Xiangge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403817/
https://www.ncbi.nlm.nih.gov/pubmed/36128521
http://dx.doi.org/10.1039/d2ra04709h
_version_ 1784773466818347008
author Xu, Yiwen
Long, Yang
Ye, Runyou
Li, Qiang
Ke, Fang
Zhou, Xiangge
author_facet Xu, Yiwen
Long, Yang
Ye, Runyou
Li, Qiang
Ke, Fang
Zhou, Xiangge
author_sort Xu, Yiwen
collection PubMed
description An Fe(iii)-catalysed transformation of secondary N-phenyl substituted amides to primary amides by an electrochemical method is developed. Regioselective aryl C–H oxygenation occurs during the reaction, promoting selective C(phenyl)-N bond cleavage to form primary amides in yields of up to 92%.
format Online
Article
Text
id pubmed-9403817
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher The Royal Society of Chemistry
record_format MEDLINE/PubMed
spelling pubmed-94038172022-09-19 Fe(iii)-catalysed selective C–N bond cleavage of N-phenylamides by an electrochemical method Xu, Yiwen Long, Yang Ye, Runyou Li, Qiang Ke, Fang Zhou, Xiangge RSC Adv Chemistry An Fe(iii)-catalysed transformation of secondary N-phenyl substituted amides to primary amides by an electrochemical method is developed. Regioselective aryl C–H oxygenation occurs during the reaction, promoting selective C(phenyl)-N bond cleavage to form primary amides in yields of up to 92%. The Royal Society of Chemistry 2022-08-25 /pmc/articles/PMC9403817/ /pubmed/36128521 http://dx.doi.org/10.1039/d2ra04709h Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Xu, Yiwen
Long, Yang
Ye, Runyou
Li, Qiang
Ke, Fang
Zhou, Xiangge
Fe(iii)-catalysed selective C–N bond cleavage of N-phenylamides by an electrochemical method
title Fe(iii)-catalysed selective C–N bond cleavage of N-phenylamides by an electrochemical method
title_full Fe(iii)-catalysed selective C–N bond cleavage of N-phenylamides by an electrochemical method
title_fullStr Fe(iii)-catalysed selective C–N bond cleavage of N-phenylamides by an electrochemical method
title_full_unstemmed Fe(iii)-catalysed selective C–N bond cleavage of N-phenylamides by an electrochemical method
title_short Fe(iii)-catalysed selective C–N bond cleavage of N-phenylamides by an electrochemical method
title_sort fe(iii)-catalysed selective c–n bond cleavage of n-phenylamides by an electrochemical method
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403817/
https://www.ncbi.nlm.nih.gov/pubmed/36128521
http://dx.doi.org/10.1039/d2ra04709h
work_keys_str_mv AT xuyiwen feiiicatalysedselectivecnbondcleavageofnphenylamidesbyanelectrochemicalmethod
AT longyang feiiicatalysedselectivecnbondcleavageofnphenylamidesbyanelectrochemicalmethod
AT yerunyou feiiicatalysedselectivecnbondcleavageofnphenylamidesbyanelectrochemicalmethod
AT liqiang feiiicatalysedselectivecnbondcleavageofnphenylamidesbyanelectrochemicalmethod
AT kefang feiiicatalysedselectivecnbondcleavageofnphenylamidesbyanelectrochemicalmethod
AT zhouxiangge feiiicatalysedselectivecnbondcleavageofnphenylamidesbyanelectrochemicalmethod

Ejemplares similares