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Heterogeneity of resistant mechanisms in an EGFR-TKI relapsed patient with EGFR amplification and response to nimotuzumab: A case report

EGFR mutations are the most important drivers of gene alterations in lung adenocarcinomas and are sensitive to EGFR-TKIs. However, resistance to EGFR-TKIs is inevitable in the majority of EGFR-mutated lung cancer patients. Numerous resistant mechanisms have been revealed to date, and more are still...

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Detalles Bibliográficos
Autores principales:	Li, Yan, Xu, Ziyi, Xie, Tongji, Xing, Puyuan, Ying, Jianming, Li, Junling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403890/ https://www.ncbi.nlm.nih.gov/pubmed/36033496 http://dx.doi.org/10.3389/fonc.2022.937282

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