Proscillaridin A induces mitochondrial damage and autophagy in pancreatic cancer and reduces the stability of SMAD4 in Panc-1 cells

BACKGROUND: Pancreatic cancer (PC) is a highly metastatic and lethal cancer with a very low overall 5-year survival rate. There is an urgent need for identifying new therapeutic agents for this deadly disease. Cardiac glycosides (CGs) have been traditionally used for their potent cardiovascular acti...

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Detalles Bibliográficos
Autores principales: Hou, Jia, Kang, Ning, Liu, Nan-Nan, Tan, Dan, Zhang, Si, Liu, Jing, Xie, Youhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403942/
https://www.ncbi.nlm.nih.gov/pubmed/36034984
http://dx.doi.org/10.21037/atm-22-1085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403942/
https://www.ncbi.nlm.nih.gov/pubmed/36034984
http://dx.doi.org/10.21037/atm-22-1085

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