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Advanced glycation end products (AGEs) downregulate the miR-4429/PTEN axis to promote apoptosis of fibroblasts in pelvic organ prolapse

BACKGROUND: Pelvic organ prolapse (POP) is a common degenerative disease among females. We previously reported that advanced glycation end products (AGEs), compounds derived from nonenzymatic glycoxidation reactions, accumulated in the human vaginal wall and impaired the function of fibroblasts in t...

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Detalles Bibliográficos
Autores principales:	Sima, Yizhen, Li, Lisha, Xiao, Chengzhen, Xu, Leimei, Wang, Ling, Chen, Yisong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403944/ https://www.ncbi.nlm.nih.gov/pubmed/36035012 http://dx.doi.org/10.21037/atm-22-628

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