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Scraping nasal cytology in the diagnostics of rhinitis and the comorbidities
Nasal scraping cytology is a non-invasive tool used in the diagnostics of allergic and non-allergic rhinitis. The study aimed to analyze to what extent the cytological picture of the nasal mucosa coincides with the diagnosis of a given disease, taking into account the content of eosinophils. Retrosp...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403955/ https://www.ncbi.nlm.nih.gov/pubmed/36008516 http://dx.doi.org/10.1038/s41598-022-18734-3 |
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author | Myszkowska, Dorota Bazgier, Monika Brońska, Sara Nowak, Karol Ożga, Joanna Woźniak, Aleksandra Stanisz, Andrzej Szaleniec, Joanna |
author_facet | Myszkowska, Dorota Bazgier, Monika Brońska, Sara Nowak, Karol Ożga, Joanna Woźniak, Aleksandra Stanisz, Andrzej Szaleniec, Joanna |
author_sort | Myszkowska, Dorota |
collection | PubMed |
description | Nasal scraping cytology is a non-invasive tool used in the diagnostics of allergic and non-allergic rhinitis. The study aimed to analyze to what extent the cytological picture of the nasal mucosa coincides with the diagnosis of a given disease, taking into account the content of eosinophils. Retrospective analysis of the cytograms performed in 842 patients was carried out in relation to the disease entities and the content of eosinophils. Significant relationship between the Epith:Infl ratio and the four groups of diseases (Chi(2) = 9.6488; p = .014) was confirmed. The more intensive inflammation was found, the higher percentage of patients had manifested the increased level of eosinophils (> 1% in the inflammatory cells). The value of 20% of eosinophils in all counted cells corresponds to around 45% of eosinophils in the inflammatory cells in patients with the evident inflammatory picture. Allergic rhinitis presents a different cytological picture regarding the eosinophilic reaction against the background of the inflammation process: the higher degree of inflammation observed, the lower amount of eosinophils detected, with the exception of allergic rhinitis provoked by pollen allergens. |
format | Online Article Text |
id | pubmed-9403955 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-94039552022-08-25 Scraping nasal cytology in the diagnostics of rhinitis and the comorbidities Myszkowska, Dorota Bazgier, Monika Brońska, Sara Nowak, Karol Ożga, Joanna Woźniak, Aleksandra Stanisz, Andrzej Szaleniec, Joanna Sci Rep Article Nasal scraping cytology is a non-invasive tool used in the diagnostics of allergic and non-allergic rhinitis. The study aimed to analyze to what extent the cytological picture of the nasal mucosa coincides with the diagnosis of a given disease, taking into account the content of eosinophils. Retrospective analysis of the cytograms performed in 842 patients was carried out in relation to the disease entities and the content of eosinophils. Significant relationship between the Epith:Infl ratio and the four groups of diseases (Chi(2) = 9.6488; p = .014) was confirmed. The more intensive inflammation was found, the higher percentage of patients had manifested the increased level of eosinophils (> 1% in the inflammatory cells). The value of 20% of eosinophils in all counted cells corresponds to around 45% of eosinophils in the inflammatory cells in patients with the evident inflammatory picture. Allergic rhinitis presents a different cytological picture regarding the eosinophilic reaction against the background of the inflammation process: the higher degree of inflammation observed, the lower amount of eosinophils detected, with the exception of allergic rhinitis provoked by pollen allergens. Nature Publishing Group UK 2022-08-25 /pmc/articles/PMC9403955/ /pubmed/36008516 http://dx.doi.org/10.1038/s41598-022-18734-3 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Myszkowska, Dorota Bazgier, Monika Brońska, Sara Nowak, Karol Ożga, Joanna Woźniak, Aleksandra Stanisz, Andrzej Szaleniec, Joanna Scraping nasal cytology in the diagnostics of rhinitis and the comorbidities |
title | Scraping nasal cytology in the diagnostics of rhinitis and the comorbidities |
title_full | Scraping nasal cytology in the diagnostics of rhinitis and the comorbidities |
title_fullStr | Scraping nasal cytology in the diagnostics of rhinitis and the comorbidities |
title_full_unstemmed | Scraping nasal cytology in the diagnostics of rhinitis and the comorbidities |
title_short | Scraping nasal cytology in the diagnostics of rhinitis and the comorbidities |
title_sort | scraping nasal cytology in the diagnostics of rhinitis and the comorbidities |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403955/ https://www.ncbi.nlm.nih.gov/pubmed/36008516 http://dx.doi.org/10.1038/s41598-022-18734-3 |
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