Cargando…

Scraping nasal cytology in the diagnostics of rhinitis and the comorbidities

Nasal scraping cytology is a non-invasive tool used in the diagnostics of allergic and non-allergic rhinitis. The study aimed to analyze to what extent the cytological picture of the nasal mucosa coincides with the diagnosis of a given disease, taking into account the content of eosinophils. Retrosp...

Descripción completa

Detalles Bibliográficos
Autores principales: Myszkowska, Dorota, Bazgier, Monika, Brońska, Sara, Nowak, Karol, Ożga, Joanna, Woźniak, Aleksandra, Stanisz, Andrzej, Szaleniec, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403955/
https://www.ncbi.nlm.nih.gov/pubmed/36008516
http://dx.doi.org/10.1038/s41598-022-18734-3
_version_ 1784773497436766208
author Myszkowska, Dorota
Bazgier, Monika
Brońska, Sara
Nowak, Karol
Ożga, Joanna
Woźniak, Aleksandra
Stanisz, Andrzej
Szaleniec, Joanna
author_facet Myszkowska, Dorota
Bazgier, Monika
Brońska, Sara
Nowak, Karol
Ożga, Joanna
Woźniak, Aleksandra
Stanisz, Andrzej
Szaleniec, Joanna
author_sort Myszkowska, Dorota
collection PubMed
description Nasal scraping cytology is a non-invasive tool used in the diagnostics of allergic and non-allergic rhinitis. The study aimed to analyze to what extent the cytological picture of the nasal mucosa coincides with the diagnosis of a given disease, taking into account the content of eosinophils. Retrospective analysis of the cytograms performed in 842 patients was carried out in relation to the disease entities and the content of eosinophils. Significant relationship between the Epith:Infl ratio and the four groups of diseases (Chi(2) = 9.6488; p = .014) was confirmed. The more intensive inflammation was found, the higher percentage of patients had manifested the increased level of eosinophils (> 1% in the inflammatory cells). The value of 20% of eosinophils in all counted cells corresponds to around 45% of eosinophils in the inflammatory cells in patients with the evident inflammatory picture. Allergic rhinitis presents a different cytological picture regarding the eosinophilic reaction against the background of the inflammation process: the higher degree of inflammation observed, the lower amount of eosinophils detected, with the exception of allergic rhinitis provoked by pollen allergens.
format Online
Article
Text
id pubmed-9403955
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-94039552022-08-25 Scraping nasal cytology in the diagnostics of rhinitis and the comorbidities Myszkowska, Dorota Bazgier, Monika Brońska, Sara Nowak, Karol Ożga, Joanna Woźniak, Aleksandra Stanisz, Andrzej Szaleniec, Joanna Sci Rep Article Nasal scraping cytology is a non-invasive tool used in the diagnostics of allergic and non-allergic rhinitis. The study aimed to analyze to what extent the cytological picture of the nasal mucosa coincides with the diagnosis of a given disease, taking into account the content of eosinophils. Retrospective analysis of the cytograms performed in 842 patients was carried out in relation to the disease entities and the content of eosinophils. Significant relationship between the Epith:Infl ratio and the four groups of diseases (Chi(2) = 9.6488; p = .014) was confirmed. The more intensive inflammation was found, the higher percentage of patients had manifested the increased level of eosinophils (> 1% in the inflammatory cells). The value of 20% of eosinophils in all counted cells corresponds to around 45% of eosinophils in the inflammatory cells in patients with the evident inflammatory picture. Allergic rhinitis presents a different cytological picture regarding the eosinophilic reaction against the background of the inflammation process: the higher degree of inflammation observed, the lower amount of eosinophils detected, with the exception of allergic rhinitis provoked by pollen allergens. Nature Publishing Group UK 2022-08-25 /pmc/articles/PMC9403955/ /pubmed/36008516 http://dx.doi.org/10.1038/s41598-022-18734-3 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Myszkowska, Dorota
Bazgier, Monika
Brońska, Sara
Nowak, Karol
Ożga, Joanna
Woźniak, Aleksandra
Stanisz, Andrzej
Szaleniec, Joanna
Scraping nasal cytology in the diagnostics of rhinitis and the comorbidities
title Scraping nasal cytology in the diagnostics of rhinitis and the comorbidities
title_full Scraping nasal cytology in the diagnostics of rhinitis and the comorbidities
title_fullStr Scraping nasal cytology in the diagnostics of rhinitis and the comorbidities
title_full_unstemmed Scraping nasal cytology in the diagnostics of rhinitis and the comorbidities
title_short Scraping nasal cytology in the diagnostics of rhinitis and the comorbidities
title_sort scraping nasal cytology in the diagnostics of rhinitis and the comorbidities
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403955/
https://www.ncbi.nlm.nih.gov/pubmed/36008516
http://dx.doi.org/10.1038/s41598-022-18734-3
work_keys_str_mv AT myszkowskadorota scrapingnasalcytologyinthediagnosticsofrhinitisandthecomorbidities
AT bazgiermonika scrapingnasalcytologyinthediagnosticsofrhinitisandthecomorbidities
AT bronskasara scrapingnasalcytologyinthediagnosticsofrhinitisandthecomorbidities
AT nowakkarol scrapingnasalcytologyinthediagnosticsofrhinitisandthecomorbidities
AT ozgajoanna scrapingnasalcytologyinthediagnosticsofrhinitisandthecomorbidities
AT wozniakaleksandra scrapingnasalcytologyinthediagnosticsofrhinitisandthecomorbidities
AT staniszandrzej scrapingnasalcytologyinthediagnosticsofrhinitisandthecomorbidities
AT szaleniecjoanna scrapingnasalcytologyinthediagnosticsofrhinitisandthecomorbidities