Role of NLRP3 Inflammasome and Its Inhibitors as Emerging Therapeutic Drug Candidate for Alzheimer’s Disease: a Review of Mechanism of Activation, Regulation, and Inhibition

Alzheimer’s disease (AD) is one of the most prevalent neurodegenerative disorders. The etiology and pathology of AD are complicated, variable, and yet to be completely discovered. However, the involvement of inflammasomes, particularly the NLRP3 inflammasome, has been emphasized recently. NLRP3 is a...

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Detalles Bibliográficos
Autores principales: Sharma, Barkha, Satija, Garvit, Madan, Anish, Garg, Mansi, Alam, M. Mumtaz, Shaquiquzzaman, M., Khanna, Suruchi, Tiwari, Prachi, Parvez, Suhel, Iqubal, Ashif, Haque, Syed Ehtaishamul, Khan, Mohammad Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403980/
https://www.ncbi.nlm.nih.gov/pubmed/36006570
http://dx.doi.org/10.1007/s10753-022-01730-0

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