Dihydroartemisinin remodels macrophage into an M1 phenotype via ferroptosis-mediated DNA damage

Lung cancer recruits tumor-associated macrophages (TAMs) massively, whose predominantly pro-tumor M2 phenotype leads to immunosuppression. Dihydroartemisinin (DHA) has been proven to remodel TAM into an anti-tumor M1 phenotype at certain concentrations in the present study, which was hypothesized to...

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Detalles Bibliográficos
Autores principales: Li, Liu-Gen, Peng, Xing-Chun, Yu, Ting-Ting, Xu, Hua-Zhen, Han, Ning, Yang, Xiao-Xin, Li, Qi-Rui, Hu, Jun, Liu, Bin, Yang, Zi-Yi, Xu, Xiang, Chen, Xiao, Wang, Mei-Fang, Li, Tong-Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403990/
https://www.ncbi.nlm.nih.gov/pubmed/36034842
http://dx.doi.org/10.3389/fphar.2022.949835

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9403990/
https://www.ncbi.nlm.nih.gov/pubmed/36034842
http://dx.doi.org/10.3389/fphar.2022.949835

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