Cargando…
Association of time of breakfast and nighttime fasting duration with breast cancer risk in the multicase-control study in Spain
Circadian nutritional behaviors, defined by the daily eating/fasting cycle, have been linked with breast cancer. This study aimed to further disentangle the association of nighttime fasting duration and time of breakfast with breast cancer risk. We analyzed data from 1,181 breast cancer cases and 1,...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404378/ https://www.ncbi.nlm.nih.gov/pubmed/36034928 http://dx.doi.org/10.3389/fnut.2022.941477 |
_version_ | 1784773624688803840 |
---|---|
author | Palomar-Cros, Anna Harding, Barbara N. Espinosa, Ana Papantoniou, Kyriaki Pérez-Gómez, Beatriz Straif, Kurt Ardanaz, Eva Fernández Villa, Tania Amiano, Pilar Gómez-Acebo, Inés Moreno, Victor Alguacil, Juan Fernández-Tardón, Guillermo Molina-Barceló, Ana Marcos-Gragera, Rafael Aragonés, Nuria Castaño-Vinyals, Gemma Guevara, Marcela Marcos Delgado, Alba Pollán, Marina Romaguera, Dora Kogevinas, Manolis |
author_facet | Palomar-Cros, Anna Harding, Barbara N. Espinosa, Ana Papantoniou, Kyriaki Pérez-Gómez, Beatriz Straif, Kurt Ardanaz, Eva Fernández Villa, Tania Amiano, Pilar Gómez-Acebo, Inés Moreno, Victor Alguacil, Juan Fernández-Tardón, Guillermo Molina-Barceló, Ana Marcos-Gragera, Rafael Aragonés, Nuria Castaño-Vinyals, Gemma Guevara, Marcela Marcos Delgado, Alba Pollán, Marina Romaguera, Dora Kogevinas, Manolis |
author_sort | Palomar-Cros, Anna |
collection | PubMed |
description | Circadian nutritional behaviors, defined by the daily eating/fasting cycle, have been linked with breast cancer. This study aimed to further disentangle the association of nighttime fasting duration and time of breakfast with breast cancer risk. We analyzed data from 1,181 breast cancer cases and 1,326 population controls from the Spanish multicase-control study (MCC-Spain), 2008–2013. We collected circadian nutritional behaviors at mid-age via a telephonic interview. We applied logistic regression to estimate odds ratios (OR) and 95% confidence intervals (CIs) for the association of nighttime fasting duration and time of breakfast with breast cancer risk in all women and stratified by menopausal status. Models were adjusted for age, center, education, family history of breast cancer, age at menarche, number of children, breastfeeding, age at first child, body mass index (BMI), contraceptive use, and hormonal replacement therapy (HRT). A later time of breakfast was associated with a non-significant increased risk of breast cancer (OR = 1.05, 95% CI: 0.95–1.16, per hour increase). This association was stronger among premenopausal women, among whom each hour later, the time of breakfast was associated with an 18% increase in breast cancer risk (OR = 1.18, 95% CI: 1.01–1.40). The association was not observed in postmenopausal women. We did not observe an association between nighttime fasting duration and breast cancer risk after adjusting for the time of breakfast. In this study, late breakfast was associated with increased breast cancer risk, especially among premenopausal women, compared with early breakfast. Aside from nutritional quality, circadian nutritional behaviors should be further studied in relation to cancer. |
format | Online Article Text |
id | pubmed-9404378 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-94043782022-08-26 Association of time of breakfast and nighttime fasting duration with breast cancer risk in the multicase-control study in Spain Palomar-Cros, Anna Harding, Barbara N. Espinosa, Ana Papantoniou, Kyriaki Pérez-Gómez, Beatriz Straif, Kurt Ardanaz, Eva Fernández Villa, Tania Amiano, Pilar Gómez-Acebo, Inés Moreno, Victor Alguacil, Juan Fernández-Tardón, Guillermo Molina-Barceló, Ana Marcos-Gragera, Rafael Aragonés, Nuria Castaño-Vinyals, Gemma Guevara, Marcela Marcos Delgado, Alba Pollán, Marina Romaguera, Dora Kogevinas, Manolis Front Nutr Nutrition Circadian nutritional behaviors, defined by the daily eating/fasting cycle, have been linked with breast cancer. This study aimed to further disentangle the association of nighttime fasting duration and time of breakfast with breast cancer risk. We analyzed data from 1,181 breast cancer cases and 1,326 population controls from the Spanish multicase-control study (MCC-Spain), 2008–2013. We collected circadian nutritional behaviors at mid-age via a telephonic interview. We applied logistic regression to estimate odds ratios (OR) and 95% confidence intervals (CIs) for the association of nighttime fasting duration and time of breakfast with breast cancer risk in all women and stratified by menopausal status. Models were adjusted for age, center, education, family history of breast cancer, age at menarche, number of children, breastfeeding, age at first child, body mass index (BMI), contraceptive use, and hormonal replacement therapy (HRT). A later time of breakfast was associated with a non-significant increased risk of breast cancer (OR = 1.05, 95% CI: 0.95–1.16, per hour increase). This association was stronger among premenopausal women, among whom each hour later, the time of breakfast was associated with an 18% increase in breast cancer risk (OR = 1.18, 95% CI: 1.01–1.40). The association was not observed in postmenopausal women. We did not observe an association between nighttime fasting duration and breast cancer risk after adjusting for the time of breakfast. In this study, late breakfast was associated with increased breast cancer risk, especially among premenopausal women, compared with early breakfast. Aside from nutritional quality, circadian nutritional behaviors should be further studied in relation to cancer. Frontiers Media S.A. 2022-08-11 /pmc/articles/PMC9404378/ /pubmed/36034928 http://dx.doi.org/10.3389/fnut.2022.941477 Text en Copyright © 2022 Palomar-Cros, Harding, Espinosa, Papantoniou, Pérez-Gómez, Straif, Ardanaz, Fernández Villa, Amiano, Gómez-Acebo, Moreno, Alguacil, Fernández-Tardón, Molina-Barceló, Marcos-Gragera, Aragonés, Castaño-Vinyals, Guevara, Marcos Delgado, Pollán, Romaguera and Kogevinas. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Nutrition Palomar-Cros, Anna Harding, Barbara N. Espinosa, Ana Papantoniou, Kyriaki Pérez-Gómez, Beatriz Straif, Kurt Ardanaz, Eva Fernández Villa, Tania Amiano, Pilar Gómez-Acebo, Inés Moreno, Victor Alguacil, Juan Fernández-Tardón, Guillermo Molina-Barceló, Ana Marcos-Gragera, Rafael Aragonés, Nuria Castaño-Vinyals, Gemma Guevara, Marcela Marcos Delgado, Alba Pollán, Marina Romaguera, Dora Kogevinas, Manolis Association of time of breakfast and nighttime fasting duration with breast cancer risk in the multicase-control study in Spain |
title | Association of time of breakfast and nighttime fasting duration with breast cancer risk in the multicase-control study in Spain |
title_full | Association of time of breakfast and nighttime fasting duration with breast cancer risk in the multicase-control study in Spain |
title_fullStr | Association of time of breakfast and nighttime fasting duration with breast cancer risk in the multicase-control study in Spain |
title_full_unstemmed | Association of time of breakfast and nighttime fasting duration with breast cancer risk in the multicase-control study in Spain |
title_short | Association of time of breakfast and nighttime fasting duration with breast cancer risk in the multicase-control study in Spain |
title_sort | association of time of breakfast and nighttime fasting duration with breast cancer risk in the multicase-control study in spain |
topic | Nutrition |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404378/ https://www.ncbi.nlm.nih.gov/pubmed/36034928 http://dx.doi.org/10.3389/fnut.2022.941477 |
work_keys_str_mv | AT palomarcrosanna associationoftimeofbreakfastandnighttimefastingdurationwithbreastcancerriskinthemulticasecontrolstudyinspain AT hardingbarbaran associationoftimeofbreakfastandnighttimefastingdurationwithbreastcancerriskinthemulticasecontrolstudyinspain AT espinosaana associationoftimeofbreakfastandnighttimefastingdurationwithbreastcancerriskinthemulticasecontrolstudyinspain AT papantonioukyriaki associationoftimeofbreakfastandnighttimefastingdurationwithbreastcancerriskinthemulticasecontrolstudyinspain AT perezgomezbeatriz associationoftimeofbreakfastandnighttimefastingdurationwithbreastcancerriskinthemulticasecontrolstudyinspain AT straifkurt associationoftimeofbreakfastandnighttimefastingdurationwithbreastcancerriskinthemulticasecontrolstudyinspain AT ardanazeva associationoftimeofbreakfastandnighttimefastingdurationwithbreastcancerriskinthemulticasecontrolstudyinspain AT fernandezvillatania associationoftimeofbreakfastandnighttimefastingdurationwithbreastcancerriskinthemulticasecontrolstudyinspain AT amianopilar associationoftimeofbreakfastandnighttimefastingdurationwithbreastcancerriskinthemulticasecontrolstudyinspain AT gomezaceboines associationoftimeofbreakfastandnighttimefastingdurationwithbreastcancerriskinthemulticasecontrolstudyinspain AT morenovictor associationoftimeofbreakfastandnighttimefastingdurationwithbreastcancerriskinthemulticasecontrolstudyinspain AT alguaciljuan associationoftimeofbreakfastandnighttimefastingdurationwithbreastcancerriskinthemulticasecontrolstudyinspain AT fernandeztardonguillermo associationoftimeofbreakfastandnighttimefastingdurationwithbreastcancerriskinthemulticasecontrolstudyinspain AT molinabarceloana associationoftimeofbreakfastandnighttimefastingdurationwithbreastcancerriskinthemulticasecontrolstudyinspain AT marcosgragerarafael associationoftimeofbreakfastandnighttimefastingdurationwithbreastcancerriskinthemulticasecontrolstudyinspain AT aragonesnuria associationoftimeofbreakfastandnighttimefastingdurationwithbreastcancerriskinthemulticasecontrolstudyinspain AT castanovinyalsgemma associationoftimeofbreakfastandnighttimefastingdurationwithbreastcancerriskinthemulticasecontrolstudyinspain AT guevaramarcela associationoftimeofbreakfastandnighttimefastingdurationwithbreastcancerriskinthemulticasecontrolstudyinspain AT marcosdelgadoalba associationoftimeofbreakfastandnighttimefastingdurationwithbreastcancerriskinthemulticasecontrolstudyinspain AT pollanmarina associationoftimeofbreakfastandnighttimefastingdurationwithbreastcancerriskinthemulticasecontrolstudyinspain AT romagueradora associationoftimeofbreakfastandnighttimefastingdurationwithbreastcancerriskinthemulticasecontrolstudyinspain AT kogevinasmanolis associationoftimeofbreakfastandnighttimefastingdurationwithbreastcancerriskinthemulticasecontrolstudyinspain |