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Remediating Desmoplasia with EGFR‐Targeted Photoactivable Multi‐Inhibitor Liposomes Doubles Overall Survival in Pancreatic Cancer

Desmoplasia is characteristic of pancreatic ductal adenocarcinoma (PDAC), which exhibits 5‐year survival rates of 3%. Desmoplasia presents physical and biochemical barriers that contribute to treatment resistance, yet depleting the stroma alone is unsuccessful and even detrimental to patient outcome...

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Detalles Bibliográficos
Autores principales: Obaid, Girgis, Bano, Shazia, Thomsen, Hanna, Callaghan, Susan, Shah, Nimit, Swain, Joseph W. R., Jin, Wendong, Ding, Xiadong, Cameron, Colin G., McFarland, Sherri A., Wu, Juwell, Vangel, Mark, Stoilova‐McPhie, Svetla, Zhao, Jie, Mino‐Kenudson, Mari, Lin, Charles, Hasan, Tayyaba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404396/
https://www.ncbi.nlm.nih.gov/pubmed/35748165
http://dx.doi.org/10.1002/advs.202104594