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Remediating Desmoplasia with EGFR‐Targeted Photoactivable Multi‐Inhibitor Liposomes Doubles Overall Survival in Pancreatic Cancer
Desmoplasia is characteristic of pancreatic ductal adenocarcinoma (PDAC), which exhibits 5‐year survival rates of 3%. Desmoplasia presents physical and biochemical barriers that contribute to treatment resistance, yet depleting the stroma alone is unsuccessful and even detrimental to patient outcome...
Autores principales: | Obaid, Girgis, Bano, Shazia, Thomsen, Hanna, Callaghan, Susan, Shah, Nimit, Swain, Joseph W. R., Jin, Wendong, Ding, Xiadong, Cameron, Colin G., McFarland, Sherri A., Wu, Juwell, Vangel, Mark, Stoilova‐McPhie, Svetla, Zhao, Jie, Mino‐Kenudson, Mari, Lin, Charles, Hasan, Tayyaba |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404396/ https://www.ncbi.nlm.nih.gov/pubmed/35748165 http://dx.doi.org/10.1002/advs.202104594 |
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