Rational Design of the Soluble Variant of l-Pipecolic Acid Hydroxylase using the α-Helix Rule and the Hydropathy Contradiction Rule

[Image: see text] The production of recombinant proteins in Escherichia coli is an important application of biotechnology. 2-Oxoglutarate-dependent l-pipecolic acid hydroxylase derived from Xenorhabdus doucetiae (XdPH) is an excellent biocatalyst that catalyzes the hydroxylation of l-pipecolic acid...

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Detalles Bibliográficos
Autores principales: Shinoda, Suguru, Itakura, Aoi, Sasano, Haruka, Miyake, Ryoma, Kawabata, Hiroshi, Asano, Yasuhisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404520/
https://www.ncbi.nlm.nih.gov/pubmed/36033675
http://dx.doi.org/10.1021/acsomega.2c04247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404520/
https://www.ncbi.nlm.nih.gov/pubmed/36033675
http://dx.doi.org/10.1021/acsomega.2c04247

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