Microglial TYROBP/DAP12 in Alzheimer’s disease: Transduction of physiological and pathological signals across TREM2

TYROBP (also known as DAP12 or KARAP) is a transmembrane adaptor protein initially described as a receptor-activating subunit component of natural killer (NK) cells. TYROBP is expressed in numerous cell types, including peripheral blood monocytes, macrophages, dendritic cells, and osteoclasts, but a...

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Detalles Bibliográficos
Autores principales: Haure-Mirande, Jean-Vianney, Audrain, Mickael, Ehrlich, Michelle E., Gandy, Sam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404585/
https://www.ncbi.nlm.nih.gov/pubmed/36002854
http://dx.doi.org/10.1186/s13024-022-00552-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404585/
https://www.ncbi.nlm.nih.gov/pubmed/36002854
http://dx.doi.org/10.1186/s13024-022-00552-w

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