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Microglial TYROBP/DAP12 in Alzheimer’s disease: Transduction of physiological and pathological signals across TREM2
TYROBP (also known as DAP12 or KARAP) is a transmembrane adaptor protein initially described as a receptor-activating subunit component of natural killer (NK) cells. TYROBP is expressed in numerous cell types, including peripheral blood monocytes, macrophages, dendritic cells, and osteoclasts, but a...
Autores principales: | Haure-Mirande, Jean-Vianney, Audrain, Mickael, Ehrlich, Michelle E., Gandy, Sam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404585/ https://www.ncbi.nlm.nih.gov/pubmed/36002854 http://dx.doi.org/10.1186/s13024-022-00552-w |
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