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Novel Gene-Correction-Based Therapeutic Modalities for Monogenic Liver Disorders

The majority of monogenic liver diseases are autosomal recessive disorders, with few being sex-related or co-dominant. Although orthotopic liver transplantation (LT) is currently the sole therapeutic option for end-stage patients, such an invasive surgical approach is severely restricted by the lack...

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Detalles Bibliográficos
Autores principales: Ghasemzad, Mahsa, Hashemi, Mahdieh, Lavasani, Zohre Miri, Hossein-khannazer, Nikoo, Bakhshandeh, Haleh, Gramignoli, Roberto, Keshavarz Alikhani, Hani, Najimi, Mustapha, Nikeghbalian, Saman, Vosough, Massoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404740/
https://www.ncbi.nlm.nih.gov/pubmed/36004917
http://dx.doi.org/10.3390/bioengineering9080392