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Decreased Levels of GSH Are Associated with Platinum Resistance in High-Grade Serous Ovarian Cancer
High-grade serous ovarian cancer (HGSOC) is the most common and aggressive OC histotype. Although initially sensitive to standard platinum-based chemotherapy, most HGSOC patients relapse and become chemoresistant. We have previously demonstrated that platinum resistance is driven by a metabolic shif...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404763/ https://www.ncbi.nlm.nih.gov/pubmed/36009263 http://dx.doi.org/10.3390/antiox11081544 |